Article
Gene-environment interactions linking air pollution and inflammation in Parkinson's disease.
Environmental research - 1 Nov 2016
Lee Pei-Chen, Raaschou-Nielsen Ole, Lill Christina M, Bertram Lars, Sinsheimer Janet S, Hansen Johnni, Ritz Beate
Abstract excerpt
Both air pollution exposure and systemic inflammation have been linked to Parkinson's disease (PD). In the PASIDA study, 408 incident cases of PD diagnosed in 2006-2009 and their 495 population controls were interviewed and provided DNA samples. Markers of long term traffic related air pollution measures were derived from geographic information systems (GIS)-based modeling. Furthermore, we genotyped functional...
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