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Article

Mitochondrial tRNA mutation with high-salt stimulation on cardiac damage: underlying mechanism associated with change of Bax and VDAC.

American journal of physiology. Heart and circulatory physiology - 1 Nov 2016

Chao Zhu, Liuyang Tian, Nan Li, Qi Chen, Zhongqi Cai, Yang Li, Yuqi Liu

Abstract excerpt

Mitochondrial transfer RNA (tRNA) mutation with high-salt stimulation can cause high blood pressure. However, the underlying mechanisms remain unclear. In the present study, we examined the potential molecular mechanisms of cardiac damage caused by mitochondrial tRNA mutation with high-salt stimulation in spontaneously hypertensive rats (SHR). Unanesthetized, 44-wk-old, male, SHR were divided into four groups:...

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Source

Identifiers

PMID: 27638882
DOI: 10.1152/ajpheart.00874.2015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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