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Article

Sarcolemmal ATP-sensitive potassium channel protects cardiac myocytes against lipopolysaccharide-induced apoptosis.

International journal of molecular medicine - 1 Sept 2016

Zhang Xiaohui, Zhang Xiaohua, Xiong Yiqun, Xu Chaoying, Liu Xinliang, Lin Jian, Mu Guiping, Xu Shaogang, Liu Wenhe

Abstract excerpt

The sarcolemmal ATP-sensitive K+ (sarcKATP) channel plays a cardioprotective role during stress. However, the role of the sarcKATP channel in the apoptosis of cardiomyocytes and association with mitochondrial calcium remains unclear. For this purpose, we developed a model of LPS-induced sepsis in neonatal rat cardiomyocytes (NRCs). The TUNEL assay was performed in order to detect the apoptosis of cardiac myocytes...

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Identifiers

PMID: 27430376
DOI: 10.3892/ijmm.2016.2664
PMCID: PMC4990318

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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