Up‐regulation of miR ‐335 and miR ‐674‐3p in the rostral ventrolateral medulla contributes to stress‐induced hypertension

Abstract excerpt

The rostral ventrolateral medulla (RVLM) is known as the vasomotor center that plays a crucial role in mediating the development of stress-induced hypertension (SIH). MicroRNAs (miRNAs) are involved in many different biological processes and diseases. However, studies that evaluated the roles of miRNAs in the RVLM during SIH do not exist. Here, we performed RNA sequencing to explore the genome-wide miRNA profiles...

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