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Article

Human Colorectal Cancer Stage-dependent Global DNA Hypomethylation of Cancer-associated Fibroblasts.

Anticancer research - 1 Sept 2016

Ling Eduard, Ringel Amit, Sigal-Batikoff Ina, Abu-Freha Naim, Vaknine Hananya, Friah Wledy, Reshef Avraham, Pinsk Ilia, Fich Alexander, Lamprecht Sergio

Abstract excerpt

BACKGROUND/AIM: Cancer-associated fibroblasts (CAFs) play an important role in tumor development and progression. The prevailing consensus favors the view that a specific epigenetic signature underpins the stable CAF phenotype. The aim of the present study was to assess global DNA methylation in CAFs during the adenoma-carcinoma sequence in non-familial sporadic human colorectal cancer (CRC). PATIENTS AND...

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Source

Identifiers

PMID: 27630288
DOI: 10.21873/anticanres.10996

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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