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Article

Dynamic Variations in Genetic Integrity Accompany Changes in Cell Fate.

Stem cells and development - 15 Nov 2016

Chen I-Chung, Hernandez Christine, Xu Xueping, Cooney Austin, Wang Yufeng, McCarrey John R

Abstract excerpt

Pluripotent stem cells hold the potential to form the basis of novel approaches to treatment of disease in vivo as well as to facilitate the generation of models for human disease, providing powerful avenues to discovery of novel diagnostic biomarkers and/or innovative drug regimens in vitro. However, this will require extensive maintenance, expansion, and manipulation of these cells in culture, which raises a...

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Identifiers

PMID: 27627671
DOI: 10.1089/scd.2016.0221
PMCID: PMC6453492

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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