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Article

Mechanisms maintaining genomic integrity in embryonic stem cells and induced pluripotent stem cells.

Experimental biology and medicine (Maywood, N.J.) - 1 Sept 2011

Tichy Elisia D

Abstract excerpt

Embryonic stem cells (ESCs) are pluripotent, self-renewing cells that are isolated during the blastocyst stage of embryonic development. Whether these cells are derived from humans, mice or other organisms, all ESCs must employ mechanisms that prevent the propagation of mutations, generated as a consequence of DNA damage, to somatic cells produced by normal programmed differentiation. Thus, the prevention of...

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Identifiers

PMID: 21768163
DOI: 10.1258/ebm.2011.011107
PMCID: PMC4077782

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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