Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dynamic instability of genomic methylation patterns in pluripotent stem cells

24 Sept 2010

Abstract excerpt

BACKGROUND: Genomic methylation patterns are established during gametogenesis, and perpetuated in somatic cells by faithful maintenance methylation. There have been previous indications that genomic methylation patterns may be less stable in embryonic stem (ES) cells than in differentiated somatic cells, but it is not known whether different mechanisms of de novo and maintenance methylation operate in pluripotent...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Pluripotent Stem Cells Research
Share to Reproductive Biology and Fertility

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20868487
DOI: 10.1186/1756-8935-3-17

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 17 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dynamic instability of genomic methylation patterns in pluripotent stem cellsPMID 20868487Read ↗

Dynamic and static maintenance of epigenetic memory in pluripotent and somatic cells.Semantic proximity Read ↗

Establishment and Maintenance of Genomic Methylation Patterns in Mouse Embryonic Stem Cells by Dnmt3a and Dnmt3bSemantic proximity Read ↗

Human Induced Pluripotent Stem Cells: From Cell Origin, Genomic Stability, and Epigenetic Memory to Translational MedicineSemantic proximity Read ↗

Plasticity in Dnmt3L-dependent and -independent modes of de novo methylation in the developing mouse embryo.Semantic proximity Read ↗

Recurrent variations in DNA methylation in human pluripotent stem cells and their differentiated derivatives.Semantic proximity Read ↗

Dynamic Variations in Genetic Integrity Accompany Changes in Cell Fate.Semantic proximity Read ↗

Rescuing DNMT1 Fails to Fully Reverse the Molecular and Functional Repercussions of Its Loss in Mouse Embryonic Stem CellsSemantic proximity Read ↗

DNA methylation in stem cell renewal and multipotencySemantic proximity Read ↗

Epigenetic Landscape of Pluripotent Stem CellsSemantic proximity Read ↗

Assessing the Safety of Human Pluripotent Stem Cells and Their Derivatives for Clinical ApplicationsSemantic proximity Read ↗

Haploinsufficiency of the paternal-effect gene Dnmt3L results in transient DNA hypomethylation in progenitor cells of the male germline.Semantic proximity Read ↗

Epigenetic reprogramming and DNA demethylationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.