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Assessing the Safety of Human Pluripotent Stem Cells and Their Derivatives for Clinical Applications

1 Jul 2017

Abstract excerpt

Pluripotent stem cells may acquire genetic and epigenetic variants during culture following their derivation. At a conference organized by the International Stem Cell Initiative, and held at The Jackson Laboratory, Bar Harbor, Maine, October 2016, participants discussed how the appearance of such variants can be monitored and minimized and, crucially, how their significance for the safety of therapeutic...

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PMID: 28700896
DOI: 10.1016/j.stemcr.2017.05.029

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