Article
Interferon-stimulated gene 15 in hepatitis B-related liver diseases.
Oncotarget - 18 Oct 2016
Hoan Nghiem Xuan, Van Tong Hoang, Giang Dao Phuong, Toan Nguyen Linh, Meyer Christian G, Bock C-Thomas, Kremsner Peter G, Song Le Huu, Velavan Thirumalaisamy P
Abstract excerpt
This study investigates the association of Interferon-stimulated gene 15 (ISG15) polymorphisms, ISG15 serum levels and expression with HBV-related liver diseases. The ISG15 promoter and the two exons of the gene were screened for polymorphisms in 766 HBV-infected patients and in 223 controls. Soluble ISG15 levels were measured by ELISA. ISG15 mRNA expression was quantified by qRT-PCR in 36 tumor and adjacent...
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