Article
IL15 polymorphism is associated with advanced fibrosis, inflammation-related biomarkers and virological response in human immunodeficiency virus/hepatitis C virus coinfection.
Liver international : official journal of the International Association for the Study of the Liver - 1 Sept 2016
Jiménez-Sousa María A, Berenguer Juan, Rallón Norma, Pineda-Tenor Daniel, Aldamiz-Echevarria Teresa, Soriano Vicente, García-Álvarez Mónica, Vazquez-Morón Sonia, Restrepo Clara, Carrero Ana, Benito José M, Resino Salvador
Abstract excerpt
BACKGROUND & AIMS: IL15 is an essential cytokine in both innate and adaptive immune response against hepatitis C virus (HCV) infection. The aim was to analyze whether IL15 rs10833 is associated with liver disease severity and response to pegylated-interferon-alpha plus ribavirin (pegIFN-alpha/RBV) therapy in human immunodeficiency virus (HIV)-/HCV-co-infected patients. METHODS: A retrospective study was performed...
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