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Evaluation of the potential therapeutic benefits of macrophage reprogramming in multiple myeloma

13 Sept 2016

Abstract excerpt

Tumor-associated macrophages (TAM) are important components of the multiple myeloma (MM) microenvironment that support malignant plasma cell survival and resistance to therapy. It has been proposed that macrophages (MØ) retain the capacity to change in response to stimuli that can restore their antitumor functions. Here, we investigated several approaches to reprogram MØ as a novel therapeutic strategy in MM....

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PMID: 27625360
DOI: 10.1182/blood-2016-01-695395

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