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Article

Active but not inactive granulomatosis with polyangiitis is associated with decreased and phenotypically and functionally altered CD56(dim) natural killer cells.

Arthritis research & therapy - 13 Sept 2016

Merkt Wolfgang, Claus Maren, Blank Norbert, Hundemer Michael, Cerwenka Adelheid, Lorenz Hanns-Martin, Watzl Carsten

Abstract excerpt

BACKGROUND: The role of natural killer (NK) cells in granulomatosis with polyangiitis (GPA) is poorly understood. We recently reported that peripheral blood NK cell percentages correlate with the suppression of GPA activity (cohort I). The purpose of the current study was to further characterize NK cell subsets, phenotype and function in a second GPA cohort (cohort II). METHODS: Peripheral blood lymphocyte...

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Identifiers

PMID: 27624647
DOI: 10.1186/s13075-016-1098-7
PMCID: PMC5022237

Genes

CCR5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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