Article
Phenotype and function of natural killer cells in systemic lupus erythematosus: excess interferon-γ production in patients with active disease.
Arthritis and rheumatism - 1 Jun 2011
Hervier Baptiste, Beziat Vivien, Haroche Julien, Mathian Alexis, Lebon Pierre, Ghillani-Dalbin Pascale, Musset Lucile, Debré Patrice, Amoura Zahir, Vieillard Vincent
Abstract excerpt
OBJECTIVE: To determine the phenotype and the functionality of natural killer (NK) cells in patients with systemic lupus erythematosus (SLE). METHODS: A total of 94 patients with SLE (91 women and 3 men) were compared with 26 healthy controls. Active SLE was defined by an SLE Disease Activity Index score≥4. Immunologic tests were performed using nonactivated and/or interleukin-2 (IL-2)-activated peripheral blood...
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