In vitro responsiveness to interleukins and theophylline of CD16+, CD56- natural killer cells in a patient with chronic granular lymphocyte disorder.

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Article

In vitro responsiveness to interleukins and theophylline of CD16+, CD56- natural killer cells in a patient with chronic granular lymphocyte disorder.

Leukemia - 1 May 1992

Bayle C, Vitté-Mony I, Lang P, Pico J, Hercend T, Bertoglio J

Abstract excerpt

We report here the case of a 55-year-old patient with chronic granular lymphocyte disorder associated with moderate neutropenia. The majority of peripheral blood lymphocytes displayed a CD3-, CD8-, CD16+, CD56(NKH1)- phenotype. The patient's cells showed high spontaneous cytotoxic activity against K562 targets and developed the ability to kill the natural killer (NK)-resistant target Daudi following activation...

Topics

Antigens, CD
Antigens, Differentiation
Antigens, Differentiation, T-Lymphocyte
CD3 Complex
CD56 Antigen
CD8 Antigens
Cell Division
Female
Humans
Interleukin-2
Interleukin-4

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Killer Cells, Lymphokine-Activated

Killer Cells, Natural

Lymphoproliferative Disorders

Middle Aged

Phenotype

Receptors, Antigen, T-Cell

Receptors, Fc

Source

Open in PubMed

Identifiers

PMID: 1375700

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1375700-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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