Article
Immune stimulatory effects of neutrophil extracellular traps in granulomatosis with polyangiitis.
Clinical and experimental rheumatology - 1 Jan 2000
Lange Christina, Csernok Elena, Moosig Frank, Holle Julia U
Abstract excerpt
OBJECTIVES: The aim of this study was to analyse the role of netting neutrophils in the pathogenesis of granulomatosis with polyangiitis (GPA), especially their interplay with peripheral blood mononuclear cells (PBMCs). METHODS: The amount of cell-free DNA (cfDNA) was determined in sera from GPA patients (pairs active/inactive state of disease, n=18) and from healthy controls (HCs, n=10). Furthermore, we...
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