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Article

Natural killer cells in patients with polycythemia vera.

Human immunology - 1 Sept 2015

Sanchez Carole, Baier Céline, Colle Julien G, Chelbi Rabie, Rihet Pascal, Le Treut Thérèse, Imbert Jean, Sébahoun Gérard, Venton Geoffroy, Costello Régis T

Abstract excerpt

Natural killer cells (NK) are pivotal cells of innate immunity. They are potent antileukemic cytotoxic effectors. A defect in their cytotoxicity has been described in some hematopoietic malignancies such as acute myeloid leukemia, multiple myeloma and myelodysplastic syndromes. This defect is at least partially linked to a decreased or absent expression of some activating NK cells molecules, more particularly the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26407910
DOI: 10.1016/j.humimm.2015.09.010

Genes

JAK2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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