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Article

Investigation of gene-diet interactions in the incretin system and risk of type 2 diabetes: the EPIC-InterAct study.

Diabetologia - 1 Dec 2016

Abstract excerpt

AIMS/HYPOTHESIS: The gut incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) have a major role in the pathophysiology of type 2 diabetes. Specific genetic and dietary factors have been found to influence the release and action of incretins. We examined the effect of interactions between seven incretin-related genetic variants in GIPR, KCNQ1, TCF7L2 and WFS1 and...

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Topics

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Share to Coffee
Share to Diabetes Mellitus, Type 2
Share to Diet

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dietary Fiber

Share to KCNQ1 Potassium Channel

Share to Membrane Proteins

Share to Proportional Hazards Models

Share to Transcription Factor 7-Like 2 Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 27623947
DOI: 10.1007/s00125-016-4090-5
PMCID: PMC6518069

Genes

GIP
GIPR
KCNQ1
WFS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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