Article
Whole-grain consumption and transcription factor-7-like 2 ( TCF7L2) rs7903146: gene-diet interaction in modulating type 2 diabetes risk.
The British journal of nutrition - 1 Feb 2009
Fisher Eva, Boeing Heiner, Fritsche Andreas, Doering Frank, Joost Hans-Georg, Schulze Matthias B
Abstract excerpt
Whole grains are known to influence postprandial glucose response and insulin demand and are inversely associated with diabetes risk. Genetic variation of the transcription factor-7-like 2 encoding gene (TCF7L2) is assumed to promote an early insulin secretory defect and has been consistently attributed to the risk of developing type 2 diabetes. The present study examined the hypothesis that the protective effect...
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