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Article

Role of TCF7L2 risk variant and dietary fibre intake on incident type 2 diabetes.

Diabetologia - 1 Oct 2012

Hindy G, Sonestedt E, Ericson U, Jing X-J, Zhou Y, Hansson O, Renström E, Wirfält E, Orho-Melander M

Abstract excerpt

AIMS/HYPOTHESIS: The T allele of transcription factor 7-like 2 gene variant, TCF7L2 rs7903146, increases the risk of type 2 diabetes by 40-50%. As TCF7L2 rs7903146 has been associated with diminished incretin effect we investigated whether interaction between dietary intake of carbohydrate, fat, protein or fibre and this variant affects the risk of type 2 diabetes. METHODS: A cohort of 24,799 non-diabetic...

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Identifiers

PMID: 22782288
DOI: 10.1007/s00125-012-2634-x
PMCID: PMC3433658

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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