Interaction of Dietary and Genetic Factors Influencing Body Iron Status and Risk of Type 2 Diabetes Within the EPIC-InterAct Study.

doi:10.2337/dc17-1080

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Interaction of Dietary and Genetic Factors Influencing Body Iron Status and Risk of Type 2 Diabetes Within the EPIC-InterAct Study.

Diabetes care - 1 Feb 2018

Meidtner Karina, Podmore Clara, Kröger Janine, van der Schouw Yvonne T, Bendinelli Benedetta, Agnoli Claudia, Arriola Larraitz, Barricarte Aurelio, Boeing Heiner, Cross Amanda J, Dow Courtney, Ekblom Kim, Fagherazzi Guy, Franks Paul W, Gunter Marc J, Huerta José María, Jakszyn Paula, Jenab Mazda, Katzke Verena A, Key Timothy J, Khaw Kay Tee, Kühn Tilman, Kyrø Cecilie, Mancini Francesca Romana, Melander Olle, Nilsson Peter M, Overvad Kim, Palli Domenico, Panico Salvatore, Quirós J Ramón, Rodríguez-Barranco Miguel, Sacerdote Carlotta, Sluijs Ivonne, Stepien Magdalena, Tjonneland Anne, Tumino Rosario, Forouhi Nita G, Sharp Stephen J, Langenberg Claudia, Schulze Matthias B, Riboli Elio, Wareham Nicholas J

Abstract excerpt

OBJECTIVE: Meat intake has been consistently shown to be positively associated with incident type 2 diabetes. Part of that association may be mediated by body iron status, which is influenced by genetic factors. We aimed to test for interactions of genetic and dietary factors influencing body iron status in relation to the risk of incident type 2 diabetes. RESEARCH DESIGN AND METHODS: The case-cohort comprised...

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PMID: 29167213
DOI: 10.2337/dc17-1080
PMCID: PMC6130703

Genes

HFE
TMPRSS6

Variants

rs1799945
rs1799945
rs1799945

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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