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Article

Structural impact analysis of missense SNPs present in the uroguanylin gene by long-term molecular dynamics simulations.

Journal of theoretical biology - 7 Dec 2016

Marcolino Antonio C S, Porto William F, Pires Állan S, Franco Octavio L, Alencar Sérgio A

Abstract excerpt

The guanylate cyclase activator 2B, also known as uroguanylin, is part of the guanylin peptide family, which includes peptides such as guanylin and lymphoguanylin. The guanylin peptides could be related to sodium absorption inhibition and water secretion induction and their dysfunction may be related to various pathologies such as chronic renal failure, congestive heart failure and nephrotic syndrome. Besides,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27620667
DOI: 10.1016/j.jtbi.2016.09.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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