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Article

Computational study of deleterious missense SNPs in the USH1G gene implicated in Usher syndrome.

Journal of biomolecular structure & dynamics - 1 Jun 2026

El Khair Kenza, Toure Madoussou, Redouane Salaheddine, Charoute Hicham, Slaoui Kenza, Benrahma Houda, Barakat Abdelhamid

Abstract excerpt

Usher syndrome is an inherited condition that causes hearing and visual impairments, along with vestibular dysfunction, due to mutations in various genes, including USH1G, which codes for the scaffold protein SANS, essential for proper sensory function. This study employed a computational approach in order to analyze the potential impact of missense SNPs in USH1G. We started by curating and filtering SNPs from...

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Share to Adaptor Proteins, Signal Transducing
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Mutation, Missense

Share to Nerve Tissue Proteins

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Source

Identifiers

PMID: 40892044
DOI: 10.1080/07391102.2025.2553345

Genes

USH1G

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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