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Article

Output without input: the lifelong productivity of hematopoietic stem cells.

Current opinion in cell biology - 1 Dec 2016

Höfer Thomas, Rodewald Hans-Reimer

Abstract excerpt

The hematopoietic stem cell (HSC) compartment must be maintained life-long, while being replenishable only from within. HSC proliferation can compensate for cell loss by differentiation, by cell death, or by mobilization from the bone marrow niches, but the relative use of proliferation to compensate for these distinct depletion sources is unclear. Classifications of HSC states (e.g., as active, dormant,...

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Identifiers

PMID: 27620508
DOI: 10.1016/j.ceb.2016.08.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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