Article
The emergence of definitive hematopoietic stem cells in the mammal
1 May 2005
Abstract excerpt
PURPOSE OF REVIEW: Hematopoietic stem cells (HSC) are the basis for blood formation during adult life. The amazing potency of HSCs has been exploited for over 30 years in regenerative therapies for patients with blood-related genetic disease and leukemia. As clinically important cells and also as the most widely studied cell differentiation system, they have been the focus of intense fundamental research. Indeed,...
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