Article
Unperturbed vs. post-transplantation hematopoiesis: both in vivo but different.
Current opinion in hematology - 1 Jul 2016
Busch Katrin, Rodewald Hans-Reimer
Abstract excerpt
PURPOSE OF REVIEW: Hematopoietic stem cell (HSC) transplantation has yielded tremendous information on experimental properties of HSCs. Yet, it remains unclear whether transplantation reflects the physiology of hematopoiesis. A limitation is the difficulty in accessing HSC functions without isolation, in-vitro manipulation and readout for potential. New genetic fate mapping and clonal marking techniques now shed...
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