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Article

Effects of ageing and senescence on pancreatic β‐cell function

1 Sept 2016

Abstract excerpt

Ageing is generally associated with deterioration of organ function and regenerative potential. In the case of pancreatic β-cells, an age-related decline in proliferative potential is well documented, and was proposed to contribute to the increased prevalence of type 2 diabetes in the elderly. The effects of ageing on β-cell function, namely glucose-stimulated insulin secretion (GSIS), have not been studied as...

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PMID: 27615132
DOI: 10.1111/dom.12719

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