Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The pancreatic β-cell in ageing: Implications in age-related diabetes

17 Jun 2022

Abstract excerpt

The prevalence of type 2 diabetes (T2D) and impaired glucose tolerance (IGT) increases with ageing. T2D generally results from progressive impairment of the pancreatic islets to adapt β-cell mass and function in the setting of insulin resistance and increased insulin demand. Several studies have shown an age-related decline in peripheral insulin sensitivity. However, a precise understanding of the pancreatic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diabetes and associated disorders
Share to Diabetes Management and Research
Share to Pancreatic function and diabetes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35724861
DOI: 10.1016/j.arr.2022.101674

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The pancreatic β-cell in ageing: Implications in age-related diabetesPMID 35724861Read ↗

Effects of ageing and senescence on pancreatic β‐cell functionSemantic proximity Read ↗

Pancreatic β-cell failure, clinical implications, and therapeutic strategies in type 2 diabetesSemantic proximity Read ↗

Pancreatic β-cell senescence in diabetes: mechanisms, markers and therapiesSemantic proximity Read ↗

Aging and stress induced β cell senescence and its implication in diabetes developmentSemantic proximity Read ↗

Senescence: a double-edged sword in beta-cell health and failure?Semantic proximity Read ↗

Pancreatic β-Cells and Type 2 Diabetes DevelopmentSemantic proximity Read ↗

Defects in β-Cell Ca2+ Dynamics in Age-Induced DiabetesSemantic proximity Read ↗

Genetic and biochemical pathways of β‐cell failure in type 2 diabetesSemantic proximity Read ↗

β-Cell Maturation and Identity in Health and Disease.Semantic proximity Read ↗

Inside the β Cell: Molecular Stress Response Pathways in Diabetes PathogenesisSemantic proximity Read ↗

Longevity of human islet α ‐ and β ‐cellsSemantic proximity Read ↗

Maintenance of β-Cell Maturity and Plasticity in the Adult PancreasSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.