Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pancreatic β-cell senescence in diabetes: mechanisms, markers and therapies

31 Aug 2023

Abstract excerpt

Cellular senescence is a response to a wide variety of stressors, including DNA damage, oncogene activation and physiologic aging, and pathologically accelerated senescence contributes to human disease, including diabetes mellitus. Indeed, recent work in this field has demonstrated a role for pancreatic β-cell senescence in the pathogenesis of Type 1 Diabetes, Type 2 Diabetes and monogenic diabetes. Small...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Birth, Development, and Health
Share to Pancreatic function and diabetes
Share to Telomeres, Telomerase, and Senescence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37720527
DOI: 10.3389/fendo.2023.1212716

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pancreatic β-cell senescence in diabetes: mechanisms, markers and therapiesPMID 37720527Read ↗

Aging and stress induced β cell senescence and its implication in diabetes developmentSemantic proximity Read ↗

Senescence: a double-edged sword in beta-cell health and failure?Semantic proximity Read ↗

Role of Cellular Senescence in Type II Diabetes.Semantic proximity Read ↗

Cellular senescence: at the nexus between ageing and diabetesSemantic proximity Read ↗

Reversing and modulating cellular senescence in beta cells, a new field of opportunities to treat diabetesSemantic proximity Read ↗

Unique Human and Mouse β-Cell Senescence-Associated Secretory Phenotype (SASP) Reveal Conserved Signaling Pathways and Heterogeneous FactorsSemantic proximity Read ↗

A human and mouse subpopulation of senescent β-cells induces pathologic dysfunction through targetable paracrine signalingSemantic proximity Read ↗

Distinct senescent β-cell senotypes differentially drive islet aging and dysfunctionSemantic proximity Read ↗

The pancreatic β-cell in ageing: Implications in age-related diabetesSemantic proximity Read ↗

Exploring senescence as a modifier of β cell extracellular vesicles in type 1 diabetesSemantic proximity Read ↗

Cellular senescence: Implications for metabolic disease.Semantic proximity Read ↗

Cellular Senescence in Ageing, Age-Related Disease and LongevitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.