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Article

Spatiotemporal microbial evolution on antibiotic landscapes.

Science (New York, N.Y.) - 9 Sept 2016

Baym Michael, Lieberman Tami D, Kelsic Eric D, Chait Remy, Gross Rotem, Yelin Idan, Kishony Roy

Abstract excerpt

A key aspect of bacterial survival is the ability to evolve while migrating across spatially varying environmental challenges. Laboratory experiments, however, often study evolution in well-mixed systems. Here, we introduce an experimental device, the microbial evolution and growth arena (MEGA)-plate, in which bacteria spread and evolved on a large antibiotic landscape (120 × 60 centimeters) that allowed visual...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27609891
DOI: 10.1126/science.aag0822
PMCID: PMC5534434

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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