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Article

Adaptive Landscapes of Resistance Genes Change as Antibiotic Concentrations Change.

Molecular biology and evolution - 1 Oct 2015

Mira Portia M, Meza Juan C, Nandipati Anna, Barlow Miriam

Abstract excerpt

Most studies on the evolution of antibiotic resistance are focused on selection for resistance at lethal antibiotic concentrations, which has allowed the detection of mutant strains that show strong phenotypic traits. However, solely focusing on lethal concentrations of antibiotics narrowly limits our perspective of antibiotic resistance evolution. New high-resolution competition assays have shown that resistant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26113371
DOI: 10.1093/molbev/msv146

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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