Article

Fluorescence photography of patterns and waves of bacterial adaptation at high antibiotic doses

2019-10-16

Abstract excerpt

Fisher suggested advantageous genes would spread through populations as a wave so we sought genetic waves in evolving populations, as follows. By fusing a fluorescent marker to a drug efflux protein (AcrB) whose expression provides Escherichia coli with resistance to some antibiotics, we quantified the evolution and spread of drug-resistant E. coli through spacetime using image analysis and quantitative PCR. As...

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Literature Corpus work: ae8fd815-63a9-565e-9c9e-f25657bb1afd
DOI: 10.1101/806232

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