Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Exploring the regulatory role of isocitrate dehydrogenase mutant protein on glioma stem cell proliferation.

European review for medical and pharmacological sciences - 1 Aug 2016

Lu H-C, Ma J, Zhuang Z, Qiu F, Cheng H-L, Shi J-X

Abstract excerpt

OBJECTIVE: Glioma is the most lethal form of cancer that originates mostly from the brain and less frequently from the spine. Glioma is characterized by abnormal regulation of glial cell differentiation. The severity of the glioma was found to be relaxed in isocitrate dehydrogenase 1 (IDH1) mutant. The present study focused on histological discrimination and regulation of cancer stem cell between IDH1 mutant and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Neoplasms
Share to Cell Proliferation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to IDH1 gene

Share to Glioma

Share to Isocitrate Dehydrogenase

Share to Mutant Proteins

Share to Mutation

Share to Neoplastic Stem Cells

Source

Identifiers

PMID: 27608896

Genes

IDH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Exploring the regulatory role of isocitrate dehydrogenase mutant protein on glioma stem cell proliferation.PMID 27608896Read ↗

IDH1 mutation diminishes aggressive phenotype in glioma stem cells.Semantic proximity Read ↗

Unraveling the tumor-promoting role of wildtype Isocitrate dehydrogenase 1 (IDH1) in human gliomasSemantic proximity Read ↗

Isocitrate dehydrogenase-mutant glioma: Evolving clinical and therapeutic implications.Semantic proximity Read ↗

Expression of CD133 Cancer Stem Cell Marker in IDH-Mutant and IDH-wildtype (Isocitrate Dehydrogenase) Astrocytoma.Semantic proximity Read ↗

Single-nucleus transcriptomics of IDH1- and TP53-mutant glioma stem cells displays diversified commitment on invasive cancer progenitorsSemantic proximity Read ↗

Molecular mechanisms involved in gliomagenesis.Semantic proximity Read ↗

Isocitrate Dehydrogenase Mutations in Glioma: From Basic Discovery to Therapeutics DevelopmentSemantic proximity Read ↗

The MRI Features and Prognosis of Gliomas Associated With IDH1 Mutation: A Single Center Study in Southwest ChinaSemantic proximity Read ↗

Molecular classification of IDH-mutant glioblastomas based on gene expression profilesSemantic proximity Read ↗

IDH-mutant gliomas arise from glial progenitor cells harboring the initial driver mutationSemantic proximity Read ↗

Weighted Gene Coexpression Network Analysis Reveals Cancer Stem Cell-Associated Metabolic Gene Signature in GliomaSemantic proximity Read ↗

IDH mutation in glioma: new insights and promises for the future.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.