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Article

Overexpression of Large-Conductance Calcium-Activated Potassium Channels in Human Glioblastoma Stem-Like Cells and Their Role in Cell Migration.

Journal of cellular physiology - 1 Sept 2017

Rosa Paolo, Sforna Luigi, Carlomagno Silvia, Mangino Giorgio, Miscusi Massimo, Pessia Mauro, Franciolini Fabio, Calogero Antonella, Catacuzzeno Luigi

Abstract excerpt

Glioblastomas (GBMs) are brain tumors characterized by diffuse invasion of cancer cells into the healthy brain parenchyma, and establishment of secondary foci. GBM cells abundantly express large-conductance, calcium-activated potassium (BK) channels that are thought to promote cell invasion. Recent evidence suggests that the GBM high invasive potential mainly originates from a pool of stem-like cells, but the...

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PMID: 27606467
DOI: 10.1002/jcp.25592

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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