Article
Novel Peripherally Derived Neural-Like Stem Cells as Therapeutic Carriers for Treating Glioblastomas.
Stem cells translational medicine - 1 Feb 2017
Birbrair Alexander, Sattiraju Anirudh, Zhu Dongqin, Zulato Gilberto, Batista Izadora, Nguyen Van T, Messi Maria Laura, Solingapuram Sai Kiran Kumar, Marini Frank C, Delbono Osvaldo, Mintz Akiva
Abstract excerpt
Glioblastoma (GBM), an aggressive grade IV astrocytoma, is the most common primary malignant adult brain tumor characterized by extensive invasiveness, heterogeneity, and angiogenesis. Standard treatment options such as radiation and chemotherapy have proven to be only marginally effective in treating GBM because of its invasive nature. Therefore, extensive efforts have been put forth to develop tumor-tropic stem...
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