Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A proinvasive role for the Ca<sup>2+</sup>‐activated K<sup>+</sup> channel KCa3.1 in malignant glioma

2 Mar 2014

Abstract excerpt

Glioblastoma multiforme are highly motile primary brain tumors. Diffuse tissue invasion hampers surgical resection leading to poor patient prognosis. Recent studies suggest that intracellular Ca(2+) acts as a master regulator for cell motility and engages a number of downstream signals including Ca(2+) -activated ion channels. Querying the REepository of Molecular BRAin Neoplasia DaTa (REMBRANDT), an annotated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiac electrophysiology and arrhythmias
Share to Ion channel regulation and function
Share to Neuroscience and Neuropharmacology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24585442
DOI: 10.1002/glia.22655

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A proinvasive role for the Ca<sup>2+</sup>‐activated K<sup>+</sup> channel KCa3.1 in malignant gliomaPMID 24585442Read ↗

Spatial Dissection of Invasive Front from Tumor Mass Enables Discovery of Novel microRNA Drivers of Glioblastoma InvasionSemantic proximity Read ↗

MAP-ing glioma invasion: Mitogen-activated protein kinase kinase 3 and p38 drive glioma invasion and progression and predict patient survivalSemantic proximity Read ↗

KCa3.1 inhibition switches the phenotype of glioma-infiltrating microglia/macrophages.Semantic proximity Read ↗

Microtubule-associated NAV3 regulates invasive phenotypes in glioblastoma cells.Semantic proximity Read ↗

Regulators of G-Protein Signaling 3 and 4 (RGS3, RGS4) Are Associated with Glioma Cell MotilitySemantic proximity Read ↗

Cost of migration: invasion of malignant gliomas and implications for treatment.Semantic proximity Read ↗

Molecular pathways triggering glioma cell invasionSemantic proximity Read ↗

Identification of a Druggable Pathway Controlling Glioblastoma InvasivenessSemantic proximity Read ↗

Role of key genetic mutations on increasing migration of brain cancer cells through confinement.Semantic proximity Read ↗

Overexpression of Large-Conductance Calcium-Activated Potassium Channels in Human Glioblastoma Stem-Like Cells and Their Role in Cell Migration.Semantic proximity Read ↗

Choice of Animal Models to Investigate Cell Migration and Invasion in GlioblastomaSemantic proximity Read ↗

Glioma invasion mediated by the p75 neurotrophin receptor (p75NTR/CD271) requires regulated interaction with PDLIM1Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.