Article
Microtubule-associated NAV3 regulates invasive phenotypes in glioblastoma cells.
Brain pathology (Zurich, Switzerland) - 1 Jan 2025
Škarková Aneta, Pelantová Markéta, Tolde Ondřej, Legátová Anna, Mateu Rosana, Bušek Petr, Garcia-Borja Elena, Šedo Aleksi, Etienne-Manneville Sandrine, Rösel Daniel, Brábek Jan
Abstract excerpt
Glioblastomas are aggressive brain tumors for which effective therapy is still lacking, resulting in dismal survival rates. These tumors display significant phenotypic plasticity, harboring diverse cell populations ranging from tumor core cells to dispersed, highly invasive cells. Neuron navigator 3 (NAV3), a microtubule-associated protein affecting microtubule growth and dynamics, is downregulated in various...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.