Article
A very low geno2pheno false positive rate is associated with poor viro-immunological response in drug-naïve patients starting a first-line HAART.
PloS one - 1 Jan 2014
Armenia Daniele, Soulie Cathia, Di Carlo Domenico, Fabeni Lavinia, Gori Caterina, Forbici Federica, Svicher Valentina, Bertoli Ada, Sarmati Loredana, Giuliani Massimo, Latini Alessandra, Boumis Evangelo, Zaccarelli Mauro, Bellagamba Rita, Andreoni Massimo, Marcelin Anne-Geneviève, Calvez Vincent, Antinori Andrea, Ceccherini-Silberstein Francesca, Perno Carlo-Federico, Santoro Maria Mercedes
Abstract excerpt
BACKGROUND: We previously found that a very low geno2pheno false positive rate (FPR ≤ 2%) defines a viral population associated with low CD4 cell count and the highest amount of X4-quasispecies. In this study, we aimed at evaluating whether FPR ≤ 2% might impact on the viro-immunological response in HIV-1 infected patients starting a first-line HAART. METHODS: The analysis was performed on 305 HIV-1 B subtype...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.