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Mood Stabilizers and the Influence on Global Leukocyte DNA Methylation in Bipolar Disorder

1 Jan 2015

Abstract excerpt

Little is known about the relationship between treatments for bipolar disorder (BD), their therapeutic responses and the DNA methylation status. We investigated whether global DNA methylation levels differ between healthy controls and bipolar patients under different treatments. Global DNA methylation was measured in leukocyte DNA from bipolar patients under lithium monotherapy (n = 29) or combination therapy (n...

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PMID: 27602359
DOI: 10.1159/000430867

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