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DNA Methylation Signatures of Mood Stabilizers and Antipsychotics in Bipolar Disorder

21 Jan 2016

Abstract excerpt

AIM: In view of the potential effects of psychiatric drugs on DNA methylation, we investigated whether medication use in bipolar disorder is associated with DNA methylation signatures. EXPERIMENTAL PROCEDURES: Blood-based DNA methylation patterns of six frequently used psychotropic drugs (lithium, quetiapine, olanzapine, lamotrigine, carbamazepine, and valproic acid) were examined in 172 bipolar disorder...

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PMID: 26792232
DOI: 10.2217/epi.15.98

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