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Article

Decreased global methylation in patients with bipolar disorder who respond to lithium.

The international journal of neuropsychopharmacology - 1 Apr 2014

Huzayyin Aya A, Andreazza Ana C, Turecki Gustavo, Cruceanu Cristiana, Rouleau Guy A, Alda Martin, Young L Trevor

Abstract excerpt

Mitochondrial dysfunction, oxidative stress, and alterations in DNA methylation, are all associated with the pathophysiology of bipolar disorder (BD). We therefore studied the relationship between oxidative stress and DNA methylation in patients with BD with an excellent response to lithium treat...

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Source

Identifiers

PMID: 24345589
DOI: 10.1017/S1461145713001569

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24345589-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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