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Methylomic Biomarkers of Lithium Response in Bipolar Disorder: A Proof of Transferability Study

23 Jan 2022

Abstract excerpt

Response to lithium (Li) is highly variable in bipolar disorders (BD) and no clinical or biological predictors of long-term response have been validated to date. Using a genome-wide methylomic approach (SeqCapEpi), we previously identified seven differentially methylated regions (DMRs) that discriminated good from non-responders (prophylactic response phenotype defined using the “Alda” scale). This study is a...

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PMID: 35215246
DOI: 10.3390/ph15020133

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