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Article

Pyrazinamide Resistance Assays and Two-Month Sputum Culture Status in Patients with Multidrug-Resistant Tuberculosis.

Antimicrobial agents and chemotherapy - 1 Nov 2016

Velásquez Gustavo E, Calderon Roger I, Mitnick Carole D, Becerra Mercedes C, Huang Chuan-Chin, Zhang Zibiao, Contreras Carmen C, Yataco Rosa M, Galea Jerome T, Lecca Leonid W, Murray Megan B

Abstract excerpt

Phenotypic drug susceptibility testing is the current "gold standard" for detecting Mycobacterium tuberculosis susceptibility to antituberculous drugs. Pyrazinamide is one antituberculous drug for which the correlation between in vitro resistance and clinical outcomes remains unclear. Here we performed latent class analysis (LCA) to develop a consensus gold standard definition of pyrazinamide resistance using...

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Identifiers

PMID: 27600032
DOI: 10.1128/AAC.00632-16
PMCID: PMC5075084

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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