Article
Authentication and characterisation of a new oesophageal adenocarcinoma cell line: MFD-1.
Scientific reports - 7 Sept 2016
Garcia Edwin, Hayden Annette, Birts Charles, Britton Edward, Cowie Andrew, Pickard Karen, Mellone Massimiliano, Choh Clarisa, Derouet Mathieu, Duriez Patrick, Noble Fergus, White Michael J, Primrose John N, Strefford Jonathan C, Rose-Zerilli Matthew, Thomas Gareth J, Ang Yeng, Sharrocks Andrew D, Fitzgerald Rebecca C, Underwood Timothy J
Abstract excerpt
New biological tools are required to understand the functional significance of genetic events revealed by whole genome sequencing (WGS) studies in oesophageal adenocarcinoma (OAC). The MFD-1 cell line was isolated from a 55-year-old male with OAC without recombinant-DNA transformation. Somatic genetic variations from MFD-1, tumour, normal oesophagus, and leucocytes were analysed with SNP6. WGS was performed in...
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