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Article

Genomic Instability of iPSCs: Challenges Towards Their Clinical Applications.

Stem cell reviews and reports - 1 Feb 2017

Yoshihara Masahito, Hayashizaki Yoshihide, Murakawa Yasuhiro

Abstract excerpt

Induced pluripotent stem cells (iPSCs) are a type of pluripotent stem cells generated directly from mature cells through the introduction of key transcription factors. iPSCs can be propagated and differentiated into many cell types in the human body, holding enormous potential in the field of regenerative medicine. However, genomic instability of iPSCs has been reported with the advent of high-throughput...

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Identifiers

PMID: 27592701
DOI: 10.1007/s12015-016-9680-6
PMCID: PMC5346115

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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