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Challenges to the clinical application of pluripotent stem cells: towards genomic and functional stability

1 Jan 2012

Abstract excerpt

Human embryonic stem cells (hESCs) can undergo unlimited self-renewal and are pluripotent, retaining the ability to differentiate into all cell types in the body. As a renewable source of various types of human cells, hESCs hold great therapeutic potential. Although significant advances have been achieved in defining the conditions needed to differentiate hESCs into various types of biologically active cells,...

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PMID: 22741526
DOI: 10.1186/gm354

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