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Article

Senescent Cells: Emerging Targets for Human Aging and Age-Related Diseases.

Trends in biochemical sciences - 1 Jul 2020

Song Shuling, Lam Eric W-F, Tchkonia Tamara, Kirkland James L, Sun Yu

Abstract excerpt

Aging is a major risk factor for numerous human pathologies, including cardiovascular, metabolic, musculoskeletal, and neurodegenerative conditions and various malignancies. While our understanding of aging is far from complete, recent advances suggest that targeting fundamental aging processes can delay, prevent, or alleviate age-related disorders. Cellular senescence is physiologically beneficial in several...

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Identifiers

PMID: 32531228
DOI: 10.1016/j.tibs.2020.03.008
PMCID: PMC7649645

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