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Article

Phenotypical Diversification of Early IFNα-Producing Human Plasmacytoid Dendritic Cells Using Droplet-Based Microfluidics.

Frontiers in immunology - 1 Jan 2021

Van Eyndhoven Laura C, Chouri Eleni, Subedi Nikita, Tel Jurjen

Abstract excerpt

Plasmacytoid dendritic cells (pDCs) are a rare type of highly versatile immune cells that besides their specialized function of massive type I interferon (IFN-I) production are able to exert cytotoxic effector functions. However, diversification upon toll like receptor (TLR)-induced activation leads to highly heterogeneous responses that have not been fully characterized yet. Using droplet-based microfluidics, we...

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Identifiers

PMID: 33995415
DOI: 10.3389/fimmu.2021.672729
PMCID: PMC8117785

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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