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Article

Evaluation of the MTHFR A1298C variant in leukoaraiosis.

Journal of molecular neuroscience : MN - 1 Mar 2012

Szolnoki Zoltan, Szaniszlo Istvan, Szekeres Marta, Hitri Krisztina, Kondacs Andras, Mandi Yvette, Nedo Erika, Somogyvari Ferenc

Abstract excerpt

Vascular demyelinization of the white matter of the brain is referred to as leukoaraiosis (LA). This very frequent entity is associated with a cognitive decline, thereby resulting in a deteriorating quality of life. Besides poorly controlled hypertension and aging, its development is reported to be associated with an elevated serum homocysteine level. Although the methylenetetrahydrofolate reductase (MTHFR) C677T...

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PMID: 21845428
DOI: 10.1007/s12031-011-9621-4

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MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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