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Article

Origin of the U87MG glioma cell line: Good news and bad news

31 Aug 2016

Abstract excerpt

Human tumor-derived cell lines are indispensable tools for basic and translational oncology. They have an infinite life span and are easy to handle and scalable, and results can be obtained with high reproducibility. However, a tumor-derived cell line may not be authentic to the tumor of origin. Two major questions emerge: Have the identity of the donor and the actual tumor origin of the cell line been accurately...

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PMID: 27582061
DOI: 10.1126/scitranslmed.aaf6853

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